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Pancreatic cancer: treatment sequence improves survival
18 février 2026

By Elodie Vaz | Published on February 18, 2026 | 3 min readLong regarded as one of the most aggressive cancers, pancreatic cancer remains associated with high mortality despite therapeutic advances. At what is considered an “early” stage, surgery has historically been proposed as first-line treatment with curative intent. However, a study conducted at the Mayo Clinic suggests that this strategy ma
By Elodie Vaz | Published on February 18, 2026 | 3 min read
Long regarded as one of the most aggressive cancers, pancreatic cancer remains associated with high mortality despite therapeutic advances. At what is considered an “early” stage, surgery has historically been proposed as first-line treatment with curative intent. However, a study conducted at the Mayo Clinic suggests that this strategy may not be optimal for a substantial proportion of patients. Published in February in the Journal of the National Comprehensive Cancer Network (JNCCN), the findings show that treatment sequence directly influences survival, particularly when the tumor is in contact with a key vessel.
Long regarded as one of the most aggressive cancers, pancreatic cancer remains associated with high mortality despite therapeutic advances. At what is considered an “early” stage, surgery has historically been proposed as first-line treatment with curative intent. However, a study conducted at the Mayo Clinic suggests that this strategy may not be optimal for a substantial proportion of patients. Published in February in the Journal of the National Comprehensive Cancer Network (JNCCN), the findings show that treatment sequence directly influences survival, particularly when the tumor is in contact with a key vessel.
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Scientific reference
Redefining Upfront Resectable Pancreatic Ductal Adenocarcinoma: Should Vein Abutment Matter?
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