By Ana Espino | Published on December 18, 2025 | 3 min readCardiovascular diseases (CVDs)
remain the leading cause of death worldwide, largely driven by
metabolic risk
factors such as hyperglycemia, dyslipidemia, hypertension, and overweight.
Although pharmacological treatments are well established, they may be associated
with
side effects or poor tolerance, particularly in patients with chronic
conditions or those receiving multiple medications.
In this context, interest in
complementary, natural, and low-cost approaches is increasing.
Cinnamon, used
for centuries in traditional medicine, has demonstrated
antioxidant,
anti-inflammatory, hypolipidemic, and hypoglycemic effects in preclinical studies.
However, clinical evidence has remained fragmented, with sometimes
contradictory results depending on populations, doses, or formulations used
(extracts, powder, oils).
This study was initiated to evaluate
the efficacy, safety, and clinical relevance of cinnamon supplementation on
major cardiovascular risk factors in adults.
Can cinnamon improve your
cardiovascular markers?
Thirty-five randomized controlled
trials, including
2,240 adult participants, were selected. The included studies
compared cinnamon supplementation with placebo or no intervention, over
durations ranging from
4 to 16 weeks, and across diverse settings (patients
with diabetes, obesity, or overweight). Cinnamon was administered in various
forms (capsules, powder, aqueous or alcoholic extracts), with doses generally
ranging from 1 to 6 g/day.
The results show
a significant
improvement in several metabolic parameters among supplemented subjects.
Cinnamon reduced fasting blood glucose, glycated hemoglobin (HbA1c), body
weight, body mass index (BMI), waist circumference, triglycerides, total cholesterol,
and LDL cholesterol. In contrast, no notable effect was observed on HDL
cholesterol or on systolic or diastolic blood pressure. These effects were
generally more pronounced in patients with type 2 diabetes or those with
metabolic syndrome, particularly when supplementation exceeded 8 weeks.
A small natural boost, but under
certain conditions
Cardiovascular diseases represent a
major public health challenge and are closely linked to
metabolic imbalances
such as hyperglycemia, dyslipidemia, and overweight. Given the limitations of
some pharmacological treatments, integrating
complementary nutritional
approaches, such as
cinnamon supplementation, is attracting growing interest.
This study aimed to rigorously
assess its
effectiveness on the main cardiovascular risk factors in adults. The
findings demonstrate a
significant improvement in several metabolic parameters,
particularly glycemic and lipid markers, thereby reinforcing the therapeutic
potential of cinnamon within a comprehensive prevention strategy.
However, limitations remain and
justify further research. Future studies should include
more homogeneous and
larger-scale clinical trials conducted over longer durations, with
standardized
formulations, dosages, and outcome measures. It will also be essential to
explore long-term safety, precise mechanisms of action, and the identification
of patient profiles most likely to benefit from this intervention.
Read next: Cinnamon: more than just a spice?
About the author – Ana EspinoPhD in Immunology, specialized in Virology
As a scientific writer, Ana is passionate about bridging the gap between research and real-world impact. With expertise in immunology, virology, oncology, and clinical studies, she makes complex science clear and accessible. Her mission: to accelerate knowledge sharing and empower evidence-based decisions through impactful communication.