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Immune cells and systemic lupus: a global dysregulation of the immune system
8 mai 2026
By Ana Espino | Published on May 8, 2026 | 4 min read
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by profound dysregulation of immune homeostasis, involving both innate and adaptive immunity. Recent advances, particularly through single-cell RNA sequencing and multi-omics approaches, have made it possible to identify specific alterations in cellular subpopulations, paving the way for more personalized medicine.
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by profound dysregulation of immune homeostasis, involving both innate and adaptive immunity. Recent advances, particularly through single-cell RNA sequencing and multi-omics approaches, have made it possible to identify specific alterations in cellular subpopulations, paving the way for more personalized medicine.
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Scientific reference
Wu Y, et al. Immune cell aberrations in Systemic Lupus Erythematosus: navigating the targeted therapies toward precision management. Cell Mol Biol Lett. 2025 Jun 16;30(1):73.
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