Clinical biomarkers are linked to accelerated ageing in patients with metabolic and cardiovascular pathologies

The article entitled ‘Factors influencing accelerated ageing in patients with type 2 diabetes mellitus and coronary heart disease’ explores the factors influencing accelerated ageing in patients with type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD).

Type 2 diabetes, as a metabolic disease, is increasingly prevalent throughout the world, representing a major public health challenge. At the same time, the combination of T2DM and CHD is also on the rise, with severe impacts on patients' health. The ageing associated with these diseases further complicates disease management and increases the risk of complications. Biological ageing acceleration, or PhenoAgeAccel, is an important measure for assessing the state of health of diabetic patients. The aim of this study was to determine the clinical indicators and biomarkers predictive of accelerated ageing in patients with T2DM and CHD.