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microRNAs to diagnose ADHD?
16 janvier 2026
By Ana Espino | Published on January 16, 2026 | 3 min readAttention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children, affecting approximately 5.2% of children worldwide. Despite this high prevalence, diagnosis relies mainly on subjective clinical assessments, which can lead to diagnostic errors or delays in management. Available treatments, a
By Ana Espino | Published on January 16, 2026 | 3 min read
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children, affecting approximately 5.2% of children worldwide. Despite this high prevalence, diagnosis relies mainly on subjective clinical assessments, which can lead to diagnostic errors or delays in management.
Available treatments, although effective for some patients, are often criticized for overuse (e.g., methylphenidate), and the lack of objective biomarkers remains a major limitation in improving care. Identifying reliable biomarkers therefore represents a key challenge for refining diagnosis and enabling more targeted treatments. The aim of this study was to evaluate the diagnostic accuracy of microRNAs (miRNAs) as markers of ADHD in children and adolescents through a systematic review and meta-analysis.
Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children, affecting approximately 5.2% of children worldwide. Despite this high prevalence, diagnosis relies mainly on subjective clinical assessments, which can lead to diagnostic errors or delays in management.
Available treatments, although effective for some patients, are often criticized for overuse (e.g., methylphenidate), and the lack of objective biomarkers remains a major limitation in improving care. Identifying reliable biomarkers therefore represents a key challenge for refining diagnosis and enabling more targeted treatments. The aim of this study was to evaluate the diagnostic accuracy of microRNAs (miRNAs) as markers of ADHD in children and adolescents through a systematic review and meta-analysis.
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Scientific reference
Diagnostic accuracy of miRNAs in attention-deficit/hyperactivity disorder: a systematic review and meta-analysis. Frontiers in Public Health, 13, 1712404
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