Chronic endometritis and recurrent reproductive failure: a systematic review and meta-analysis

The endometrium plays a crucial role in reproduction by promoting blastocyst adhesion, cytotrophoblast invasion and foetal development. Among the various uterine disorders, endometritis, particularly chronic endometritis, has attracted attention due to its association with adverse reproductive outcomes (recurrent pregnancy loss, recurrent implantation failure and infertility).

The association between chronic endometritis and adverse reproductive outcomes highlights the need for comprehensive diagnostic and therapeutic strategies to optimise fertility outcomes and support individuals on their journey to parenthood.