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Fibers and kidneys: the hidden solution?
10 mars 2025
#Fiber #UremicToxins #Inflammation #Microbiota #Nutrition #KidneyDisease #Dialysis
Patients with chronic kidney disease (CKD) often suffer from an imbalance in the gut microbiota, known as dysbiosis. This disruption promotes the proliferation of bacteria that break down dietary proteins and produce uremic toxins (p-cresyl sulfate, indoxyl sulfate, TMAO). Since the kidneys cannot effectively eliminate these toxins, they accumulate in the body, leading to chronic inflammation and worsening disease progression.
Patients with chronic kidney disease (CKD) often suffer from an imbalance in the gut microbiota, known as dysbiosis. This disruption promotes the proliferation of bacteria that break down dietary proteins and produce uremic toxins (p-cresyl sulfate, indoxyl sulfate, TMAO). Since the kidneys cannot effectively eliminate these toxins, they accumulate in the body, leading to chronic inflammation and worsening disease progression.
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Scientific reference
Wathanavasin, W., et al. (2025). Effects of Dietary Fiber Supplementation on Modulating Uremic Toxins and Inflammation in Chronic Kidney Disease Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Toxins, 17(2), 57
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