Remote ischemic conditioning in acute ischemic stroke

Remote ischemic conditioning is a neuroprotective strategy developed to prevent and treat ischemic stroke, but its efficacy and safety in acute ischemic stroke are controversial. In this systematic review and meta-analysis, researchers evaluated the efficacy and safety of remote ischemic conditioning in patients receiving different treatments. In all, the researchers included data from 22 trials, involving 7,657 patients. Compared with the control group, patients who received remote ischemic conditioning had no improvement in functional outcomes, whether they received medical management, reperfusion therapy with intravenous thrombolysis or mechanical thrombectomy.