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Can physical exercise improve quality of life in patients with metastatic castration-resistant prostate cancer?
19 novembre 2025
By Lila Rouland | Published on November 19, 2025 | 3 min readMetastatic castration-resistant prostate cancer (mCRPC) represents an advanced stage of the disease, commonly treated with androgen deprivation therapy (ADT). Although this strategy improves survival, it often leads to a deterioration in quality of life (QoL), with side effects such as fatigue, cognitive impairment, bone pain, and urinar
Metastatic castration-resistant prostate cancer (mCRPC) represents an advanced stage of the disease, commonly treated with androgen deprivation therapy (ADT). Although this strategy improves survival, it often leads to a deterioration in quality of life (QoL), with side effects such as fatigue, cognitive impairment, bone pain, and urinary or sexual dysfunction. These physical symptoms are compounded by the psychological burden of living with a chronic, incurable condition.
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Scientific reference
Quality of life for men with metastatic castrate-resistant prostate cancer participating in an aerobic and resistance exercise pilot intervention. Langlais CS, et al. Urologic Oncology: Seminars and Original Investigations. 2023;41(2):146.e1–146.e11.
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