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Childhood obesity: could homocysteine be the key?

6 mars 2025

Childhood obesity: could homocysteine be the key?
#ChildHealth  #Metabolism  #VitaminB12  #Folate  #Homocysteine  #Obesity


Childhood obesity is a rapidly growing public health concern worldwide. According to the WHO, the number of overweight or obese children and adolescents has increased tenfold in recent decades. This rise is linked to lifestyle changes, including increased consumption of ultra-processed foods and decreased physical activity.

The balance between vitamin B12, folates, and homocysteine (Hcy) plays a crucial role in maintaining overall health. These biomarkers are key players in DNA synthesis and protein metabolism. They also contribute to inflammation regulation, which is essential for children's growth and development.

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Scientific reference

Ulloque-Badaracco, J. R., et al. (2025). Vitamin B12, folate, and homocysteine levels in children and adolescents with obesity: a systematic review and meta-analysis. Frontiers in public health, 13, 1481002

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