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Cerebral pH and lactates in neuropsychiatric disorders

1 avril 2024

Cerebral pH and lactates in neuropsychiatric disorders

Increased lactate levels have been suggested as a biomarker of metabolic changes during neuronal excitation. These changes in lactate levels can lead to a decrease in brain pH, a trend observed in patients with various…

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Scientific reference

Hideo Hagihara et al. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. Elife. 2024 Mar 26:12:RP89376

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