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When hepatitis becomes hepatocellular carcinoma
29 juillet 2025
By Lila Rouland | Published on July 29, 2025 | 3 min read
#viralhepatitis #hepatocellularcarcinoma #oncology #biomarkers #inflammation
Introduction: chronic hepatitis, a driver of hepatocellular carcinoma
Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, is primarily caused by chronic infection with hepatitis B virus (HBV) or hepatitis C virus (HCV). These infections lead to persistent liver inflammation, oxidative stress, fibrosis, and ultimately malignant transformation. Despite advances in antiviral treatments and targeted therapies, major challenges remain, including drug resistance and the lack of reliable biomarkers for patient stratification.
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Scientific reference
Yuan, H., (2025). The malignant transformation of viral hepatitis to hepatocellular carcinoma: Mechanisms and Interventions. MedComm, Mar 8;6(3):e70121.
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