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Zika: A Latent Threat or a Past Danger?
11 mars 2026
By Ana Espino | Published on March 11, 2026 | 3 min readZika virus (ZIKV), an arbovirus primarily transmitted by Aedes aegypti, caused a major epidemic in Latin America between 2015 and 2018, with more than 500,000 reported cases and an unexpected rise in congenital malformations, particularly microcephaly. Since 2017, global incidence has declined. However, the virus remains endemic in 92 countri
By Ana Espino | Published on March 11, 2026 | 3 min read
Zika virus (ZIKV), an arbovirus primarily transmitted by Aedes aegypti, caused a major epidemic in Latin America between 2015 and 2018, with more than 500,000 reported cases and an unexpected rise in congenital malformations, particularly microcephaly.
Since 2017, global incidence has declined. However, the virus remains endemic in 92 countries, with particularly high risk in Latin America and the Caribbean. Recent outbreaks in Asia in 2024 highlight the persistence of epidemic potential.
The absence of an approved vaccine or specific antiviral treatment remains a major limitation, particularly for pregnant women and immunocompromised patients. This review, published in 2025 in Current Opinion in HIV and AIDS, provides a global update on epidemiology, transmission, diagnosis, clinical manifestations, and recent preventive advances.
Zika virus (ZIKV), an arbovirus primarily transmitted by Aedes aegypti, caused a major epidemic in Latin America between 2015 and 2018, with more than 500,000 reported cases and an unexpected rise in congenital malformations, particularly microcephaly.
Since 2017, global incidence has declined. However, the virus remains endemic in 92 countries, with particularly high risk in Latin America and the Caribbean. Recent outbreaks in Asia in 2024 highlight the persistence of epidemic potential.
The absence of an approved vaccine or specific antiviral treatment remains a major limitation, particularly for pregnant women and immunocompromised patients. This review, published in 2025 in Current Opinion in HIV and AIDS, provides a global update on epidemiology, transmission, diagnosis, clinical manifestations, and recent preventive advances.
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Scientific reference
de Jong HK, et al. Zika virus: an overview update. Curr Opin HIV AIDS. 2025 May 1;20(3):294-302. doi: 10.1097/COH.0000000000000926. Epub 2025 Mar 17. PMID: 40048580; PMCID: PMC11970592
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