Press review
The essentials of recent medical publications, unpacked by our newsroom into a clear, sourced digest, specialty by specialty.
PediatricsOral-pharyngeal administration of breast milk in preterm infants
The aim of this study was to evaluate the effect of bucco-pharyngeal administration of breast milk on nutritional outcomes in preterm infants. A total of 80 preterm infants were included in the study and randomly assigned to the intervention group (breast milk) and the control group (sterile water as placebo). Analyses showed that the mean volume of total milk received by the infants and the mean
Gastroenterology and HepatologyAnalgesic opioids in acute pancreatitis
The impact of analgesic treatment on short-term outcomes in acute pancreatitis remains unknown. In this study, researchers evaluated the association between analgesics, particularly opioids, and severity and mortality in hospitalized patients with acute pancreatitis. A total of 1,768 patients, managed in 118 centers in 27 countries, were included in the study. Of these, 59% received opioids on the
PsychiatryPanic disorder and Alzheimer's disease
Observational studies have suggested a link between panic disorder and Alzheimer's disease. Using two-sample Mendelian randomization analyses, researchers explored the causal links between these two conditions. The analyses provide evidence of a potential causal relationship between panic disorder and an increased risk of developing Alzheimer's disease. Extensive sensitivity analyses confirmed the
OncologyEpigenetics and angiogenesis in the tumor microenvironment
In the randomized Phase 2 trial, investigators studied the efficacy of combining the monoclonal antibody sintilimab with the histone deacetylase inhibitor chidamide (HDACi) with or without the monoclonal antibody bevacizumab in patients with chemotherapy-refractory unresectable colorectal cancer with stable/effective microsatellite mismatch repair (MSS/pMMR). A total of 48 patients were randomly a
Cardiology and Vascular MedicineSweetened beverages and atrial fibrillation
While studies have shown an association between sweetened beverages and several cardio-metabolic diseases, their link with atrial fibrillation remains to be clarified. In this study of 201,856 patients, free of atrial fibrillation at inclusion, researchers assessed the association between the risk of atrial fibrillation and the consumption of sweetened beverages, sweetened drinks and pure fruit ju
Public Health and Social MedicineEfficiency and cost of hospitalization at home
In this Cochrane review, researchers have determined the effectiveness and cost of managing patients at home, compared with hospital-based care. This publication represents the 4th update of the review. In all, data from 20 trials involving 3,100 patients were included in the analysis. Of these trials, 4 involved COPD patients, 2 involved stroke patients and 7 involved acutely ill, elderly patient
Radiodiagnostics and Medical ImagingIntestinal stenosis in Crohn's disease
Intestinal stenosis in Crohn's disease most often affects the terminal ileum and represents a clinical challenge. Imaging techniques such as intestinal ultrasound, CT enterography and magnetic resonance enterography allow assessment of the entire intestinal wall and associated peri-enteric findings. In this systematic review, researchers provide a detailed summary of the definitions, diagnosis and
Endocrinology and MetabolismAnemia in patients with type 2 diabetes and renal failure
In this prospective cohort study, investigators evaluated and compared the incidence of anemia in 13,799 patients with type 2 diabetes and renal failure (stages 1-3), initiating treatment with SGLT2 inhibitors or GLP-1 analogues. After the median follow-up period of 2.5 years, patients treated with SGLT2 inhibitors had a lower incidence of anemia than patients treated with GLP1 analogues. However,
NeurologyBatoclimab in myasthenia gravis
In this multicenter randomized clinical trial conducted from September 15, 2021 to June 29, 2022 at 27 centers in China, investigators evaluated the efficacy and safety profile of batoclimab, an anti-IgG1 monoclonal antibody, in myasthenia gravis. A total of 178 adult patients with myasthenia gravis were screened, 132 were randomly assigned, 131 tested positive for antibodies and 1 tested negative
InfectiologyInflammatory rheumatism and Covid-19
Studies suggest a higher incidence of autoimmune inflammatory rheumatic diseases in patients infected with SARS-CoV2. In this binational, longitudinal, matched cohort study, researchers included data from 10,027,506 Korean and 12,218,680 Japanese patients aged 20 years or older, including those with Covid-19 between January 1, 2020 and December 31, 2021, matched with patients with influenza infect
Physical Medicine and RehabilitationTelerehabilitation for shoulder disorders
In this systematic literature review and meta-analysis, researchers quantitatively compared telerehabilitation and home exercise in patients with shoulder disorders. A total of 7 studies, including 508 participants, were included. Compared with home exercise, telerehabilitation showed superior improvements in range of motion (flexion, abduction, external rotation, internal rotation), shoulder func
Urology-nephrologyThe microbiota in the progression of renal failure
The gut microbiota is known to affect the systemic inflammatory state and progression of kidney disease. In this study, researchers evaluated the links between key biomarkers of chronic kidney disease and altered gut microbiota following antibiotic treatment. The study involved 61 patients, for whom 59 plasma metabolites were assessed for their role in the transition from acute to chronic renal fa