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Breast cancer: a decade that transformed treatment

2 octobre 2026

Breast cancer: a decade that transformed treatment
Over the past decade, breast cancer management has undergone profound changes. The introduction of CDK4/6 inhibitors, therapies targeting the PI3K/AKT/mTOR pathway, new anti-HER2 treatments, immunotherapy, and antibody–drug conjugates (ADCs) has progressively shifted treatment toward an approach guided by the molecular characteristics of each tumor. A review published in Cancers in 2026 looks back at this decade of innovation and examines the major clinical trials and molecular advances that have shaped this evolution.

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Scientific reference

Dynarowicz K, Bartusik-Aebisher D, Czech S, Kawczyk-Krupka A, Aebisher D. A Decade of Innovation in Breast Cancer (2015–2025): A Comprehensive Review of Clinical Trials, Targeted Therapies and Molecular Perspectives. Cancers. 2026;18:361.