The origin of infantile hemangioma

Infantile hemangioma is a benign soft-tissue tumor common in infants. Its pathogenesis remains poorly understood. To find out more, researchers conducted a retrospective study of 83 pairs of twins, affected by infantile hemangioma between 2016 and 2022. Of the twin pairs included in the study, both twins in 31 pairs had infantile hemangioma, while only one twin in the other pairs had a benign tumor. The occurrence of an infantile hemangioma in both twins appeared to be correlated with the use of assisted reproduction, gender and prematurity. There was no association with zygocity or total birth weight. Nevertheless, the twin with a lower birth weight than the other had an increased risk of developing an infantile hemangioma.