Effects of faecal microbiota transplantation on gut phage communities in a clinical trial to treat adolescent obesity

FMT (Fecal Microbiota Transplantation) is a therapeutic intervention used to treat diseases associated with the gut microbiome, and phages play a crucial role in modulating the bacterial communities of the microbiota.

Intestinal phages influence human health by modulating the bacterial communities of the microbiota. Successful engraftment of donor phages correlates with the efficacy of FMT treatment. However, the effect of FMT on recipient phage populations and, consequently, on the gut environment is not yet well understood.