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Pharmacological inhibition of ASK-1 in cirrhosis

26 février 2024

Apoptosis signal-regulating kinase 1 (ASK1) is activated by various pathological stimuli and induces cell apoptosis via activation of p38. In this study, researchers evaluated the effect of pharmacological…

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Scientific reference

: Zhenwei Peng et al. ASK1/p38 axis inhibition blocks the release of mitochondrial "danger signals" from hepatocytes and suppresses progression to cirrhosis and liver cancer. Hepatology. 2024 Feb 20.

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