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ctDNA: promise of precision or reflection of inequality?

24 octobre 2025

ctDNA: promise of precision or reflection of inequality?

By Ana Espino | Published on October 24, 2025 | 3 min readBreast cancer is the most common malignancy among women worldwide. Despite major therapeutic advances, a substantial proportion of patients remain at risk of relapse, particularly those with residual disease after neoadjuvant therapy. Residual disease is a strong prognostic factor for early recurrence, especially in aggressive subtypes such

By Ana Espino | Published on October 24, 2025 | 3 min read


Breast cancer is the most common malignancy among women worldwide. Despite major therapeutic advances, a substantial proportion of patients remain at risk of relapse, particularly those with residual disease after neoadjuvant therapy. Residual disease is a strong prognostic factor for early recurrence, especially in aggressive subtypes such as triple-negative breast cancer (TNBC) and HER2-positive disease. Early detection of residual disease or imminent recurrence is therefore a critical challenge for improving personalized care and overall survival.  

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Scientific reference

Aronson, J., et al. (2025). Bridging the gap: ctDNA, genomics, and equity in breast cancer care. NPJ breast cancer, 11(1), 92

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