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HBV: Immunity asleep or awakened?

29 juillet 2025

HBV: Immunity asleep or awakened?
By Ana Espino | Published on July 29, 2025 | 3 min read


#HepatitisB #Immunity #InfectiousDiseases
 


Chronic hepatitis B (CHB) remains a major public health issue, affecting more than 296 million people worldwide. Despite the implementation of effective vaccination campaigns, the hepatitis B virus (HBV) continues to cause severe liver complications, including cirrhosis and hepatocellular carcinoma.

Current treatment relies on two main approaches: pegylated interferon (PEG-IFN-

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Scientific reference

: Shu, Y., et al. (2025). Anti-HBV treatment partially restores the dysfunction of innate immune cells and unconventional T cells during chronic HBV infection. Frontiers in immunology, 16, 1611976

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