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The fat that saves babies: spotlight on the role of BMP8B in cold resistance

12 septembre 2025

The fat that saves babies: spotlight on the role of BMP8B in cold resistance
By Lila Rouland | Published September 12, 2025 | 3 min read


#BrownAdiposeTissue #NewbornHealth #Endocrinology #Pediatrics #Metabolism #MetabolicAdaptation #ClinicalResearch #Infants #BMP8B #NeonatalPhysiology
 


Neonatal hypothermia remains a major health issue, particularly during the transition from the intrauterine to the external environment. While the role of brown adipose tissue (BAT) in heat production has long been recognized in newborns, its underlying physiological mechanisms remained poorly understood. This innovative study uses non-invasive infrared thermal imaging (IRT) to analyze BAT activity in infants while also examining key hormonal markers, including bone morphogenetic protein 8B (BMP8B), in early thermal regulation.


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Scientific reference

Urisarri, A., et al. (2025). BMP8 and activated brown adipose tissue in human newborns. Nat Commun. 2021 Sep 6;12(1):5274

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