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Kidney diseases: discovery of a “conductor” that worsens disease progression
27 avril 2026
By Elodie Vaz | Published on April 27, 2026 | 3 min readChronic kidney disease (CKD) affects more than 10% of the global population, representing nearly 850 million people. It is characterized by a progressive and irreversible decline in kidney function, which may ultimately require dialysis or transplantation. While its risk factors—such as diabetes, hypertension, obesity, and inflammation—are we
By Elodie Vaz | Published on April 27,
2026 | 3 min read
Chronic kidney disease (CKD) affects more than 10% of the global population, representing nearly 850 million people. It is characterized by a progressive and irreversible decline in kidney function, which may ultimately require dialysis or transplantation. While its risk factors—such as diabetes, hypertension, obesity, and inflammation—are well established, one particularly concerning feature remains: even when the initial cause is treated, the disease almost always continues to progress. This self-sustaining nature, long poorly understood, represents a major challenge in clinical management.
Chronic kidney disease (CKD) affects more than 10% of the global population, representing nearly 850 million people. It is characterized by a progressive and irreversible decline in kidney function, which may ultimately require dialysis or transplantation. While its risk factors—such as diabetes, hypertension, obesity, and inflammation—are well established, one particularly concerning feature remains: even when the initial cause is treated, the disease almost always continues to progress. This self-sustaining nature, long poorly understood, represents a major challenge in clinical management.
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Scientific reference
HNF1B intègre des signaux dans une boucle d’avance qui favorise la progression de la maladie rénale
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