Press review
The essentials of recent medical publications, unpacked by our newsroom into a clear, sourced digest, specialty by specialty.
OthersObesity and heart failure: weight loss may restore heart muscle contractility
By Elodie Vaz | Published on April 30, 2026 | 4 min readLong described as a disease of ventricular stiffness, heart failure with preserved ejection fraction (HFpEF) may, in patients with severe obesity, involve a distinct mechanism: an intrinsic impairment of heart muscle contraction. This is the finding of a study conducted by researchers at Johns Hopkins Medicine and published on April 23 in *Sc
OncologyLocalized lung cancer: a new triplet therapy shows promising signs of efficacy
By Elodie Vaz | Published on April 29, 2026 | 4 min readPresented during an oral session at the American Association for Cancer Research (AACR) congress held from April 17 to 22 by Prof. Fabrice Barlesi, the phase II MATISSE study brings new hope for the management of localized and operable non–small cell lung cancer (NSCLC). By adding an innovative molecule to the current standard combining chemo
GynecologyCan stress during pregnancy erase the benefits of exercise ?
By Elodie Vaz | Published on April 29, 2026 | 4 min readPregnancy is a key period of “developmental programming,” during which the maternal environment can have lasting effects on a child’s health. It is already known that physical activity during pregnancy improves the offspring’s metabolism, notably by reducing the risk of obesity and energy balance disorders. Conversely, prenatal stress is susp
OncologyAdvanced lung cancer: toward tailored treatments
By Elodie Vaz | Published on April 28, 2026 | 4 min readLung cancer remains one of the leading causes of cancer-related death worldwide. Among these tumors, non–small cell lung cancer (NSCLC) accounts for nearly 85% of diagnoses. While immunotherapy and targeted therapies have transformed patient care in recent years, a significant proportion of patients still reach a therapeutic dead end after st
HematologyAcute myeloid leukemia: targeting the CD81 protein to prevent relapse
By Elodie Vaz | Published on April 28, 2026 | 3 min readAcute myeloid leukemia (AML) is the most common form of acute leukemia in adults, with incidence increasing after the age of 60. This hematologic malignancy is characterized by uncontrolled proliferation of immature cells—blasts—in the bone marrow and peripheral blood, disrupting normal hematopoiesis. Despite recent therapeutic advances, prog
OthersKidney diseases: discovery of a “conductor” that worsens disease progression
By Elodie Vaz | Published on April 27, 2026 | 3 min readChronic kidney disease (CKD) affects more than 10% of the global population, representing nearly 850 million people. It is characterized by a progressive and irreversible decline in kidney function, which may ultimately require dialysis or transplantation. While its risk factors—such as diabetes, hypertension, obesity, and inflammation—are we
InfectiologyMalaria Vaccine: Finally a Turning Point ?
By Ana Espino | Published on April 23, 2026 | 4 min readMalaria remains a major infectious disease, responsible for hundreds of millions of cases and around 600,000 deaths each year, mainly among young children in Africa. Despite existing prevention and treatment strategies, such as mosquito nets, insecticides, and antimalarial therapies, their effectiveness is limited by the emergence of resistan
NeurologyAlzheimer’s disease: tau protein spreads along neural networks
By Elodie Vaz | Published on April 24, 2026 | 3 min readAlzheimer’s disease, the most common form of dementia, is characterized by progressive neurodegeneration. It initially affects memory, then gradually impairs all cognitive functions, ultimately compromising daily independence. Biologically, two major lesions are involved: extracellular deposits of beta-amyloid peptides and intracellular aggre
NeurologyChildhood dementia: synaptic hyperactivity as an early trigger in a brain in decline
By Elodie Vaz | Published on Avril 23, 2026 | 3 min readSanfilippo syndrome, a common form of childhood dementia, is a rare genetic disease characterized by progressive and fatal neurodegeneration. Affected children initially develop normally before rapidly losing cognitive abilities, language, and motor skills. Early clinical signs—hyperactivity, sleep disturbances, erratic behavior—precede an in
Medical GeneticsMale brain, female brain: invisible differences that may impact our mental health
By Elodie Vaz | Published on April 23, 2026 | 3 min readPsychiatric and neurological disorders—from ADHD to schizophrenia, including depression and Alzheimer’s disease—show marked differences depending on biological sex. Men and women, defined respectively by XY and XX chromosomes, are not equal in the face of these conditions, whether in terms of prevalence, age of onset, or progression. While th
GynecologyPregnancy and Malaria : A High-Risk Combination
By Ana Espino | Published on April 23, 2026 | 4 min readMalaria during pregnancy represents a major public health issue, particularly in endemic areas. This condition poses significant risks for both the mother and the fetus. Infection can lead to severe, even fatal forms, and is notably characterized by the sequestration of the parasite in the placenta, resulting in maternal anemia, intrauterine
InfectiologyCRISPR Against Malaria: The End of the Mosquito?
By Ana Espino | Published on April 22, 2026 | 4 min readMalaria is one of the deadliest infectious diseases in the world, responsible for approximately 600,000 deaths per year and transmitted by mosquitoes of the Anopheles genus. This disease has profoundly shaped human history and remains a major public health challenge today. Despite significant progress, current strategies have notable limitati