Press reviews
Hemophilia is a genetic bleeding disorder caused by a deficiency in factor VIII (hemophilia A) or factor IX (hemophilia B), leading to spontaneous or prolonged bleeding. It primarily affects males due to its X-linked inheritance and represents a chronic condition that significantly impacts quality of life.
Current tr...
Hemophilia is a rare genetic disorder characterized by a deficiency in coagulation factor VIII (hemophilia A) or IX (hemophilia B). This condition leads to recurrent bleeding episodes that can result in severe complications such as joint damage, chronic pain, and, in some cases, life-threatening hemorrhages. Beyond its clinica...
Chagas disease, or American trypanosomiasis, is a parasitic infection caused by Trypanosoma cruzi, mainly transmitted by blood-feeding insect vectors. It progresses in two phases: an acute phase that is often asymptomatic, followed by a chronic phase that, in some patients, can lead to severe and potentially fatal cardiac or...
Chagas disease is a parasitic infection caused by Trypanosoma cruzi, affecting approximately 6–7 million people worldwide, mainly in Latin America. It is characterized by an acute phase followed by a chronic infection that can last a lifetime and, in about 30% of patients, progress to severe cardiac or digestive complications....
2026-04-16
Influenza: a recombinant vaccine improves immune response in patients with severe obesity
Infectiology
A major viral infection, seasonal influenza is responsible each year for severe complications and hospitalizations, particularly among vulnerable populations. Among them, people living with severe obesity (defined as a BMI ≥ 35 kg/m²) represent a high-risk group that remains insufficiently characterized in vaccine trials....
Dementia encompasses a range of progressive cognitive disorders affecting memory, reasoning, and independence. It represents a major public health challenge in the context of global population aging.
While biological and environmental risk factors such as age, comorbidities, and level of education ar...
2026-04-14
Gut–microbiome dialogue: the unexpected role of epithelial cells
Gastroenterology and Hepatology
Interactions between the gut and the intestinal microbiome are essential for proper physiological function. These interactions largely rely on the immune system, which regulates the coexistence between the host and microbial communities.
However, these mechanisms remain poorly understood during early life,...
2026-04-13
Dietary fiber and the microbiome: a key duo still impaired in celiac disease
Gastroenterology and Hepatology
Celiac disease is an autoimmune condition triggered by gluten ingestion, leading to chronic inflammation of the small intestine. This damage alters the intestinal mucosa and impairs nutrient absorption. The only treatment is a strict gluten-free diet, which generally controls symptoms but does not fully restore intestina...
Allergies to domestic animals—particularly cats, dogs, and horses—are a major cause of allergic rhinitis and asthma, especially in children. Exposure to allergens is frequent and widespread, even in the absence of direct contact with animals, due to passive transfer mechanisms.
Diagnostic strategies mainl...
2026-04-10
Vitamin D and the microbiome: toward immune reprogramming in ibd
Gastroenterology and Hepatology
Inflammatory bowel diseases (IBD), including Crohn’s disease and ulcerative colitis, affect millions of patients worldwide. These conditions are characterized by chronic inflammation of the gastrointestinal tract, partly driven by an inappropriate immune response directed against normally tolerated intestinal bacteria.
Multiple sclerosis (MS) is a chronic and disabling neurological disease characterized by an immune-mediated attack on the central nervous system (CNS). This autoimmune response primarily targets myelin, a protective sheath essential for proper nerve impulse conduction.
At the root of this dysregulation is the immune...
Parkinson’s disease is a chronic neurodegenerative disorder characterized by the progressive worsening of motor symptoms. As the disease advances, a large majority of patients treated with levodopa develop motor fluctuations, marked by unpredictable alternations between “ON” and “OFF” periods. These fluctuations lead to signif...
Parkinson’s disease is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons and the accumulation of protein aggregates. Despite therapeutic advances, the underlying molecular mechanisms remain only partially understood.
The protein LRRK2 (leucine-rich repeat kinase 2) is now rec...
Parkinson’s disease is a major progressive neurodegenerative disorder affecting more than 8.5 million people worldwide. Its incidence continues to rise, making it an increasing public health concern. The disease is characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra, along with the accu...
2026-04-03
Gut microbiota: metabolites at the heart of cardiovascular risk
Cardiology and Vascular Medicine Gastroenterology and Hepatology
Coronary heart disease remains the leading cause of mortality worldwide. Its development relies on a complex interplay of genetic, metabolic, and environmental factors. Among these, the role of the gut microbiota has attracted growing interest. Acting as a true metabolic organ, it produces a wide range of molecules capable of...