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2024-02-20

ACE inhibitors, ARB2 inhibitors and statins at risk of pneumonia

Geriatrics

In this Italian study, researchers evaluated the effect of ACE inhibitors, ARB-2s and/or statins on the risk of pneumonia and on the risk of short-term in-hospital and outpatient mortality in patients with pneumonia. A total of 5,717 patients were included in the study, all at least 65 years of age. Of these, 18% had pneumonia and 51% were taking ACE inhibitors, ARB-2s and/or statins. An inverse association was found between treatment with ACE inhibitors or ARB-2s and pneumonia. The effect was greater when antihypertensive treatment was combined with a statin.

Source(s) :
Carlotta Franchi et al. Statins, ACE/ARBs drug use, and risk of pneumonia in hospitalized older patients: a retrospective cohort study. Intern Emerg Med. 2024 Feb 14. ;

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