Naltrexone in pregnancy

In this prospective case study, 7 pregnant women addicted to opioids (4 women) or alcohol (3 women) were treated with extended-release naltrexone. They were followed throughout their pregnancy (mean gestational age at inclusion 21.7 weeks) and up to 12 months after delivery. None of the women in the study resumed opioid use, while two resumed alcohol use. All women gave birth vaginally at a mean gestational age of 37 weeks. 71.4% of participants were still being treated with naltrexone 12 months after delivery. No fetal anomalies were observed and no premature deliveries were recorded. No infants developed neonatal opioid withdrawal syndrome.