Acanthamoeba keratitis

In this retrospective study, researchers sought to identify the risk factors and clinical features of Acanthamoeba keratitis, among all cases of infectious keratitis. A total of 134 eyes (from 126 patients) were studied, including 24 cases of Acanthamoeba keratitis, 22 cases of bacterial keratitis, 24 cases of fungal keratitis, 32 cases of herpetic keratitis and 32 cases of bacterial co-infection. Contact lens wear was observed in 24.6% of cases. Of the patients with Acanthamoeba keratitis, 73% were under 39 years of age and 73% were women. In 100% of cases of Acanthamoeba keratitis, the researchers found an epithelial defect. Endothelial plaques were found in over 69% of cases, and radial keratoneuritis in over 46%.