IL-41 in resistance to Kawasaki disease treatments

In this study, researchers examined the importance of IL-41 in clinical parameters and treatment resistance in Kawasaki disease. A total of 93 children with the disease were included. Serum IL-41 levels were significantly increased in children resistant to Kawasaki disease treatments. Serum IL-41 levels were positively correlated with erythrocyte sedimentation rate, C-reactive protein and C-reactive protein/albumin ratio, but negatively correlated with albumin. Total number of fever days and neutrophil/lymphocyte ratio were independent predictors of resistance to intravenous immunoglobulin.