Predicting lesion volume in primary hyperparathyroidism

Primary hyperparathyroidism is a surgically treated endocrine disorder. Researchers assume a correlation between lesion size and preoperative clinical data. In this study, researchers attempted to predict lesion volume from preoperative clinical data. Removed parathyroid gland volume was used as the primary endpoint, and associations with preoperative clinical data were assessed by multivariate analysis. A positive correlation was identified between parathyroid tumor volume and preoperative intact parathyroid hormone and calcium values. Multiple regression analysis revealed that male gender, intact PTH and calcium values were significant predictors of lesion volume.