What kind of brain damage is involved in long Covid?

In long Covid, many symptoms are neurological, but the underlying brain disturbances remain poorly understood. In this study, researchers recruited 89 patients with persistent neurological symptoms after Covid-19 and 22 controls who had Covid-19 without persistent neurological symptoms. The data highlighted that 48% of patients with long Covid had episodic memory deficits, and 27% also had impaired global cognitive function, particularly attention, working memory, processing speed and verbal fluency. Compared with cured controls, patients with persistent neurological symptoms had a thinner cerebral cortex in the left posterior superior temporal gyrus. Other cerebral abnormalities were observed in these patients.