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Chagas: the parasite that outsmarts the immune system?
17 avril 2026

By Ana Espino | Published on April 17, 2026 | 4 min readChagas disease, or American trypanosomiasis, is a parasitic infection caused by Trypanosoma cruzi, mainly transmitted by blood-feeding insect vectors. It progresses in two phases: an acute phase that is often asymptomatic, followed by a chronic phase that, in some patients, can lead to severe and potentially fatal cardiac or digestive complic
Chagas disease, or American trypanosomiasis, is a parasitic infection caused by Trypanosoma cruzi, mainly transmitted by blood-feeding insect vectors. It progresses in two phases: an acute phase that is often asymptomatic, followed by a chronic phase that, in some patients, can lead to severe and potentially fatal cardiac or digestive complications. Today, several million people remain infected, primarily in Latin America, although the disease is becoming increasingly global due to migration and environmental changes.
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Scientific reference
Serrano-Coll H. Chagas disease: host responses, parasite evasion and vaccine advances. Trans R Soc Trop Med Hyg. 2026 Feb 2;120(2):95-106. doi: 10.1093/trstmh/traf109. PMID: 41048042; PMCID: PMC12863075.
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