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Gene therapy: a turning point for parkinson’s disease?

7 avril 2026

Gene therapy: a turning point for parkinson’s disease?

By Ana Espino | Published on April 7, 2026 | 4 min readParkinson’s disease is a major progressive neurodegenerative disorder affecting more than 8.5 million people worldwide. Its incidence continues to rise, making it an increasing public health concern. The disease is characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra, along with the accumulation of α-sy

By Ana Espino | Published on April 7, 2026 | 4 min read


Parkinson’s disease is a major progressive neurodegenerative disorder affecting more than 8.5 million people worldwide. Its incidence continues to rise, making it an increasing public health concern. The disease is characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra, along with the accumulation of α-synuclein aggregates, leading to neuronal dysfunction.  

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Scientific reference

Szunyogh S, et al. Recent developments in gene therapy for Parkinson's disease. Mol Ther. 2025 May 7;33(5):2052-2064. doi: 10.1016/j.ymthe.2025.03.030. Epub 2025 Mar 22. PMID: 40121531; PMCID: PMC12126811

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