Press reviews
2025-08-22
Anesthesia and the brain: mere sleep or true disruption?
Anesthesia and Intensive Care Neurology
By Ana Espino | Published on August 22, 2025 | 2 min read
#POCD #Neurology #Anesthesia #Surgery
Postoperative cognitive decline (POCD) is a frequent and concerning complication, particularly among elderly patients undergoing major surgery. This condition manifests as impairments in memory, attention, or processing speed, which may durably impact quality of life...
#POCD #Neurology #Anesthesia #Surgery
Postoperative cognitive decline (POCD) is a frequent and concerning complication, particularly among elderly patients undergoing major surgery. This condition manifests as impairments in memory, attention, or processing speed, which may durably impact quality of life...
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2025-08-21
Single-cell epigenomic rewiring in alzheimer’s disease progression and cognitive resilience
Neurology
By Lila Rouland | Published on August 21, 2025 | 2 min read
#Alzheimer #CognitiveResilience
Alzheimer’s disease (AD) remains the leading cause of dementia, characterized by progressive memory loss and neuronal degeneration. While the accumulation of amyloid plaques and tau tangles is well established, the epigenetic mechanisms underlying neuronal vulnerability and resilien...
#Alzheimer #CognitiveResilience
Alzheimer’s disease (AD) remains the leading cause of dementia, characterized by progressive memory loss and neuronal degeneration. While the accumulation of amyloid plaques and tau tangles is well established, the epigenetic mechanisms underlying neuronal vulnerability and resilien...
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By Ana Espino | Published on August 21, 2025 | 2 min read
#Schizophrenia #Neuroinflammation #Cytokines
Schizophrenia is a chronic and disabling psychiatric disorder, affecting about 1% of the global population. It manifests through disorganized thinking, impaired social and occupational functioning, and a marked reduction in quality of life. Biologically, schizop...
#Schizophrenia #Neuroinflammation #Cytokines
Schizophrenia is a chronic and disabling psychiatric disorder, affecting about 1% of the global population. It manifests through disorganized thinking, impaired social and occupational functioning, and a marked reduction in quality of life. Biologically, schizop...
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2025-08-20
CDK6 inhibits de novo lipogenesis in white adipose tissue but not in the liver
Allergology and Immunology Endocrinology and Metabolism
By Lila Rouland | Published on august 20, 2025 | 3 min read
#DeNovoLipogenesis #WhiteAdiposeTissue #Obesity #Type2Diabetes #LipidMetabolism
This study explores the role of CDK6 (Cyclin-dependent kinase 6) in regulating de novo lipogenesis (DNL)—the synthesis of fatty acids from non-lipid precursors. DNL in white adipose tissue (WAT) is linked to improved insuli...
#DeNovoLipogenesis #WhiteAdiposeTissue #Obesity #Type2Diabetes #LipidMetabolism
This study explores the role of CDK6 (Cyclin-dependent kinase 6) in regulating de novo lipogenesis (DNL)—the synthesis of fatty acids from non-lipid precursors. DNL in white adipose tissue (WAT) is linked to improved insuli...
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By Ana Espino | Published on August 20, 2025 | 2 min read
#APOE #Aging #GeneticFactor
Normal aging is accompanied by progressive cognitive and biological changes, distinct from the alterations observed in neurodegenerative diseases such as Alzheimer’s disease. However, the molecular mechanisms governing this process remain incompletely understood. Current approa...
#APOE #Aging #GeneticFactor
Normal aging is accompanied by progressive cognitive and biological changes, distinct from the alterations observed in neurodegenerative diseases such as Alzheimer’s disease. However, the molecular mechanisms governing this process remain incompletely understood. Current approa...
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By Ana Espino | Published on August 18, 2025 | 2 min read
#CD146 #Immunology #RespiratoryDisease #Immunotherapy
Respiratory diseases are among the leading causes of morbidity and mortality worldwide, affecting millions of people every year and creating a substantial socio-economic burden. They encompass a wide range of pathologies of inflammatory, tu...
#CD146 #Immunology #RespiratoryDisease #Immunotherapy
Respiratory diseases are among the leading causes of morbidity and mortality worldwide, affecting millions of people every year and creating a substantial socio-economic burden. They encompass a wide range of pathologies of inflammatory, tu...
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By Ana Espino | Published on August 19, 2025 | 2 min read
#Influenza #Bronchiectasis
Bronchiectasis is a chronic lung disease characterized by irreversible dilation of the bronchi, leading to mucus accumulation, persistent inflammation, and increased susceptibility to respiratory infections. Despite therapeutic advances, management remains limited by the challenge...
#Influenza #Bronchiectasis
Bronchiectasis is a chronic lung disease characterized by irreversible dilation of the bronchi, leading to mucus accumulation, persistent inflammation, and increased susceptibility to respiratory infections. Despite therapeutic advances, management remains limited by the challenge...
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By Ana Espino | Published on August 14, 2025 | 2 min read
#Schizophrenia #CognitiveFunction #MetabolicDisorder
Schizophrenia is a severe psychiatric disorder characterized by psychotic symptoms, cognitive impairments, and global disruption of social and occupational functioning. Among its many associated comorbidities, metabolic disorders—particularly impaired gl...
#Schizophrenia #CognitiveFunction #MetabolicDisorder
Schizophrenia is a severe psychiatric disorder characterized by psychotic symptoms, cognitive impairments, and global disruption of social and occupational functioning. Among its many associated comorbidities, metabolic disorders—particularly impaired gl...
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By Ana Espino | Published on August 13, 2025 | 3 min read
#Obesity #IntermittentFasting #Nutrition
Obesity is a chronic, multifactorial disease that is steadily increasing worldwide, now affecting more than 650 million adults. It is strongly associated with an increased risk of type 2 diabetes, cardiovascular diseases, certain cancers, and a wide range of metabolic and fu...
#Obesity #IntermittentFasting #Nutrition
Obesity is a chronic, multifactorial disease that is steadily increasing worldwide, now affecting more than 650 million adults. It is strongly associated with an increased risk of type 2 diabetes, cardiovascular diseases, certain cancers, and a wide range of metabolic and fu...
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By Ana Espino | Published on August 13, 2025 | 2 min read
#AlcoholUseDisorder #AUD #Sleep #PhysicalActivity
Alcohol Use Disorder (AUD) is a chronic condition characterized by excessive and persistent alcohol consumption, often accompanied by severe disruptions in sleep and circadian rhythms. These disturbances are common and can persist even after alcohol withdraw...
#AlcoholUseDisorder #AUD #Sleep #PhysicalActivity
Alcohol Use Disorder (AUD) is a chronic condition characterized by excessive and persistent alcohol consumption, often accompanied by severe disruptions in sleep and circadian rhythms. These disturbances are common and can persist even after alcohol withdraw...
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By Ana Espino | Published on August 12, 2025 | 3 min read
#Impetigo #MRSA #Ozenoxacin #Dermatology
Impetigo is a highly contagious bacterial skin infection, common in pediatrics but also affecting adults, particularly in situations of close contact or when the skin barrier is compromised. It most often presents as erythematous lesions covered with honey-colored...
#Impetigo #MRSA #Ozenoxacin #Dermatology
Impetigo is a highly contagious bacterial skin infection, common in pediatrics but also affecting adults, particularly in situations of close contact or when the skin barrier is compromised. It most often presents as erythematous lesions covered with honey-colored...
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By Ana Espino | Published on August 11, 2025 | 2 min read
#Anaphylaxis #Allergy #Adrenaline #AAI
Anaphylaxis is a rapid-onset, potentially fatal systemic hypersensitivity reaction triggered by allergens such as foods (peanuts, tree nuts, shellfish, milk, egg), drugs, or insect venoms. Symptoms can appear within seconds and progress to airway obstruction or cardio...
#Anaphylaxis #Allergy #Adrenaline #AAI
Anaphylaxis is a rapid-onset, potentially fatal systemic hypersensitivity reaction triggered by allergens such as foods (peanuts, tree nuts, shellfish, milk, egg), drugs, or insect venoms. Symptoms can appear within seconds and progress to airway obstruction or cardio...
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By Ana Espino | Published on August 08, 2025 | 3 min read
#Gut #Microbiota #GutBrainAxis
Neurodevelopmental disorders such as autism, depression, and anxiety represent a growing challenge in mental health. Their multifactorial origins—combining genetic, environmental, and immune factors—complicate the development of effective treatments. While traditional neuropsychiat...
#Gut #Microbiota #GutBrainAxis
Neurodevelopmental disorders such as autism, depression, and anxiety represent a growing challenge in mental health. Their multifactorial origins—combining genetic, environmental, and immune factors—complicate the development of effective treatments. While traditional neuropsychiat...
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By Ana Espino | Published on August 07, 2025 | 3 min read
#Tebentafusp #Melanoma #Immunotherapy
Uveal melanoma is a rare intraocular tumor, accounting for 3–5% of all melanomas. It is characterized by a high hepatic metastatic tropism and a marked resistance to conventional systemic therapies. Despite effective local treatment options (radiotherapy, surg...
#Tebentafusp #Melanoma #Immunotherapy
Uveal melanoma is a rare intraocular tumor, accounting for 3–5% of all melanomas. It is characterized by a high hepatic metastatic tropism and a marked resistance to conventional systemic therapies. Despite effective local treatment options (radiotherapy, surg...
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By Ana Espino | Published on August 06, 2025 | 2 min read
#Fibrinogen #Hemorrhage #Coagulopathy
Traumatic hemorrhage is a leading cause of preventable death in patients suffering from severe trauma, particularly in the first few hours after injury. It is often worsened by acute coagulopathy, which arises within minutes of the trauma and contributes to increased b...
#Fibrinogen #Hemorrhage #Coagulopathy
Traumatic hemorrhage is a leading cause of preventable death in patients suffering from severe trauma, particularly in the first few hours after injury. It is often worsened by acute coagulopathy, which arises within minutes of the trauma and contributes to increased b...
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