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Thanks to advances in diagnosis and treatment, life expectancy for patients with congenital heart disease has increased in recent years. However, these patients still have a high morbidity and mortality rate. In this study, researchers described the frailty and cognitive profile of middle-aged and older adults with congenital heart disease. In all, they included 814 patients aged at least 40, living in 11 different countries. Of all patients, 41.9% were considered pre-fragile and 5.8% frail, based on the results of the Fried method. Frailty was associated with advanced age, female gender and comorbidities. Surprisingly, high complexity of cardiac disease seemed to protect against frailty.

Source(s) :
Bo Daelman et al. Frailty and Cognitive Function in Middle-Aged and Older Adults With Congenital Heart Disease. J Am Coll Cardiol. 2024 Mar 26;83(12):1149-1159. ;

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