Press review
The essentials of recent medical publications, unpacked by our newsroom into a clear, sourced digest, specialty by specialty.
OncologyCLL: ESMO declares the end of chemotherapy, focus on targeted therapies
By Lila Rouland | Published September 24, 2025 | 3 min read#ChronicLymphocyticLeukemia #TargetedTherapies #ESMO Clinicians had long debated: should high-risk CLL be treated earlier, even without symptoms? The idea was appealing—using targeted therapies at early stages to control the disease before it progresses. This was precisely tested in the CLL12 trial, which compared ibrutinib (a BTK inhibito
Public Health and Social MedicinePhysical exercise and immunity: allies or adversaries?
By Ana Espino | Published on september 23, 2025 | 3 min read #PublicHealth #Immunity #PhysicalActivity #ImmuneSystem The immune system is the body’s first line of defense against pathogens, whether bacteria, viruses, or tumor cells. Its proper functioning depends on many factors, including age, stress, nutrition, sleep… and physical activity, whose effects on immunity are generating growing intere
Public Health and Social MedicineSport & immunity: does the right dosage make the difference?
By Ana Espino | Published on september 23, 2025 | 3 min read#Immunity #PhysicalActivity #HealthPrevention #PublicHealth The immune system is a cornerstone of human health, ensuring the body’s protection against pathogens. Its proper functioning can be compromised by stress, aging, sedentary behavior, or poor lifestyle habits. In response to these disruptions, medicine often proposes pharmacologica
HematologyChronic myelomonocytic leukemia: at the molecular roots of inflammation
By Lila Rouland | Published September 22, 2025 | 3 min read#Hematology #ChronicLymphocyticLeukemia Chronic myelomonocytic leukemia (CMML) is a rare clonal hematologic disorder that lies at the crossroads between myelodysplastic syndromes and myeloproliferative neoplasms. It occurs mainly in older adults (median age >70 years) and is characterized by persistent monocytosis and a high risk (15–20% a
OncologyCMML: finally a target in sight?
By Ana Espino | Published on september 22, 2025 | 3 min read#Leukemia #CMML #CD123 #Tagraxofusp Chronic myelomonocytic leukemia (CMML) is a rare and aggressive malignant blood disorder, characterized by clonal proliferation of monocytes and marked clinical heterogeneity. It mainly affects older individuals, carries a high risk of transformation into acute myeloid leukemia, and remains associated w
Medical GeneticsAlzheimer’s: a question of genetic timing?
By Ana Espino | Published on september 21, 2025 | 3 min read #Alzheimer #Genetics #Neurology Alzheimer’s disease is a progressive neurodegenerative disorder responsible for irreversible cognitive decline, linked to abnormal accumulation of amyloid and tau proteins in the brain. While early-onset familial forms are caused by rare genetic mutations, most cases are sporadic, shaped by a complex inter
NeurologyAlzheimer’s in a drop of blood?
By Ana Espino | Published on september 21, 2025 | 3 min read#Alzheimer #Tau #Neurology Alzheimer’s disease is a progressive neurodegenerative disorder, responsible for irreversible cognitive decline and loss of autonomy, associated with the abnormal accumulation of beta-amyloid and phosphorylated tau in the brain. It is the leading cause of dementia worldwide. Diagnosis still relies heavily on inv
Allergology and ImmunologyNB-UVB: light that heals?
By Ana Espino | Published on september 19, 2025 | 3 min read#Vitiligo #Immunity #Phototherapy #NB-UVB Vitiligo — a chronic autoimmune disease — is characterized by progressive depigmentation of the skin, caused by the destruction of melanocytes. Although not life-threatening, this condition has a profound psychological and social impact, especially in younger patients. Despite the wide range of ex
Endocrinology and MetabolismTyG Index: a new ally against PCOS?
By Ana Espino | Published on september 18, 2025 | 3 min read#PCOS #Endocrinology #Metabolism #TyGIndex Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age, affecting up to 15–20% of this population. Although it has been extensively studied, its pathophysiological mechanisms remain only partially understood, particularly regarding the metabolic dis
GeriatricsOsteoarthritis and Ayurveda: balance restored?
By Ana Espino | Published on september 17, 2025 | 3 min read#Osteoarthritis #Ayurveda Primary knee osteoarthritis is a common degenerative condition, causing chronic pain, joint stiffness, and functional loss, with a major impact on patients’ quality of life. Despite the range of available treatments, conventional options remain largely symptomatic: analgesics, anti-inflammatory drugs, or injectio
GeriatricsValgus brace: effective but tolerable?
By Ana Espino | Published on september 17, 2025 | 3 min read#Osteoarthritis #Brace #Geriatrics Medial femorotibial osteoarthritis, or medial knee osteoarthritis, is a common chronic condition characterized by cartilage degeneration associated with biomechanical imbalance of the knee, often worsened by varus alignment. This configuration leads to overload of the medial compartment, causing pain, fu
PsychiatryVirtual reality: a weapon against stigma?
By Ana Espino | Published on september 16, 2025 | 3 min read#VirtualReality #MentalDisorders #Psychiatry Mental disorders, although highly prevalent, remain strongly stigmatized, even within environments that are supposed to be better informed, such as healthcare students. This stigma contributes to delays in seeking care, worsens social isolation, and perpetuates persistent prejudices. Traditiona